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Peptide record

TPDB30640

Neurotoxin Toxicity standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB30640
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia
standard
No
A 49-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and Peptipedia, with an available 3D structural model.
Sequence
FFECTLECDIKKEGKPCKPKGCKCNDKDNKDHKKCSGGWRCKLKLCLKF
Physicochemical Analysis
C246H400N70O68S8
AQMYV
K
5682.79
8.96
15
7
9
+7
17.96
-1.000
39.80
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6000
105.58
12
Residue Composition
number
0
A
1
R
2
N
4
D
8
C
3
E
0
Q
4
G
1
H
1
I
4
L
13
K
0
M
3
F
2
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 4 C: 8 E: 3 Q: 0 G: 4 H: 1 I: 1 L: 4 K: 13 M: 0 F: 3 P: 2 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
49
C246H400N70O68S8
5682.79
8.96
+7
17.96
-1.000
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Toxin that causes irreversible contractile paralysis into adult Aedes aegypti resulting in 100% mortality after 24 hours. {ECO:0000250|UniProtKB:P0DRD8}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Lasiodora parahybana (Brazilian salmon pink birdeater) (Brazilian salmon pink tarantula)
Neurotoxin
Toxin that causes irreversible contractile paralysis into adult Aedes aegypti resulting in 100% mortality after 24 hours..
U1-theraphotoxin-Lp1b (U1-TRTX-Lp1b) (Lasiotoxin-2) (LpTX2)
spider
Neurotoxin 12 (Hwtx-2) family, 04 (lasiotoxin) subfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 12 (Hwtx-2) family, 04 (lasiotoxin) subfamily
U1-theraphotoxin-Lp1b (U1-TRTX-Lp1b) (Lasiotoxin-2) (LpTX2)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
spider