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Peptide record

TPDB30555

Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB30555
Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 20-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
EWGRRCCGWGPGRRYCVRWC
Physicochemical Analysis
C107H156N38O24S4
ANDQHILKMFST
R
2486.90
9.27
5
1
5
+4
-0.82
-0.950
14.50
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
18240
733.44
5
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
1
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
3
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 1 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 3 Y: 1 V: 1
Chemical Descriptors
20
C107H156N38O24S4
2486.90
9.27
+4
-0.82
-0.950
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>400 µM
Hemolytic Cytotoxic
10% Hemolysis | >400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial specificity and mechanism of action of disulfide-removed linear analogs of the plant-derived Cys-rich antimicrobial peptide Ib-AMP1. | Peptides | 2009