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Peptide record

TPDB30425

Neurotoxin Toxicity standard
76 amino acids
Basic Information
3D PDB MODEL
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TPDB30425
Neurotoxin Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 76-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
EIPQNLGSDIPHDIIKLPNGQWCKTPGALCSSRSECCKAKHSDSVTYSSGCSRQWSDQQGLFINQCRTCNVESSMC
Physicochemical Analysis
C348H551N105O117S9
S
8366.38
6.85
9
7
18
-0
16.37
-0.576
56.45
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
12990
155.26
34
Residue Composition
number
2
A
3
R
4
N
4
D
8
C
3
E
6
Q
5
G
2
H
5
I
4
L
4
K
1
M
1
F
4
P
12
S
3
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 4 D: 4 C: 8 E: 3 Q: 6 G: 5 H: 2 I: 5 L: 4 K: 4 M: 1 F: 1 P: 4 S: 12 T: 3 W: 2 Y: 1 V: 2
Chemical Descriptors
76
C348H551N105O117S9
8366.38
6.85
-0
16.37
-0.576
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Neurotoxin with probable ion channel impairing activity. In vivo, is both paralytic and lethal, when injected into lepidopteran larvae. {ECO:0000269|PubMed:1440641}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Apomastus schlingeri (Trap-door spider) (Aptostichus schlingeri)
Neurotoxin Ion channel impairing toxin
Neurotoxin with probable ion channel impairing activity. In vivo, is both paralytic and lethal, when injected into lepidopteran larvae..
U1-cyrtautoxin-As1d (U1-CUTX-As1d) (Aptotoxin IX) (Aptotoxin-9) (Paralytic peptide IX) (PP IX)
spider
Neurotoxin 21 family
Evidence at protein level
Direct protein sequencing Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:1440641}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Neurotoxin 21 family
U1-cyrtautoxin-As1d (U1-CUTX-As1d) (Aptotoxin IX) (Aptotoxin-9) (Paralytic peptide IX) (PP IX)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:1440641}.
spider