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Peptide record

TPDB30302

Neurotoxin Toxicity standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB30302
Neurotoxin Toxicity
Toxicity and safety peptides
Peptipedia
standard
No
A 65-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ECSKQLGESCKCNKQCCGATVICGTIYVGGKEENLCIEKTSNNAILNFFGKIAHVVENGLSFSCD
Physicochemical Analysis
C294H473N81O97S8
RMPW
C
6950.95
5.58
7
7
20
-1
14.80
-0.015
76.46
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
1990
28.63
25
Residue Composition
number
3
A
0
R
6
N
1
D
8
C
6
E
2
Q
7
G
1
H
5
I
4
L
6
K
0
M
3
F
0
P
5
S
3
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 3 R: 0 N: 6 D: 1 C: 8 E: 6 Q: 2 G: 7 H: 1 I: 5 L: 4 K: 6 M: 0 F: 3 P: 0 S: 5 T: 3 W: 0 Y: 1 V: 4
Chemical Descriptors
65
C294H473N81O97S8
6950.95
5.58
-1
14.80
-0.015
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Intrathorax injection into crickets causes paralysis prolonged for more than 60 minutes, followed by recovery. {ECO:0000269|PubMed:15246762}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Macrothele gigas (Japanese funnel web spider)
Neurotoxin
Intrathorax injection into crickets causes paralysis prolonged for more than 60 minutes, followed by recovery..
U15-hexatoxin-Mg1a (U15-HXTX-Mg1a) (Neurotoxin magi-15)
spider
Neurotoxin 25 family, F7 subfamily
Evidence at protein level
Disulfide bond Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland.
Additional Detail Fields 7 fields
Disulfide bond Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 25 family, F7 subfamily
U15-hexatoxin-Mg1a (U15-HXTX-Mg1a) (Neurotoxin magi-15)
TISSUE SPECIFICITY: Expressed by the venom gland.
spider