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Peptide record

TPDB29739

Neurotoxin Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB29739
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
DDLHPFNENNMYYGCKGLSNSNKFED
Physicochemical Analysis
C131H187N35O46S2
ARQITWV
N
3052.25
4.20
3
5
7
-3
7.77
-1.346
30.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
2980
97.63
10
Residue Composition
number
0
A
0
R
5
N
3
D
1
C
2
E
0
Q
2
G
1
H
0
I
2
L
2
K
1
M
2
F
1
P
2
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 5 D: 3 C: 1 E: 2 Q: 0 G: 2 H: 1 I: 0 L: 2 K: 2 M: 1 F: 2 P: 1 S: 2 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
26
C131H187N35O46S2
3052.25
4.20
-3
7.77
-1.346
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Binds to sodium channels (Nav) and affects the channel activation process. {ECO:0000250}.

Target

voltage-gated sodium channel (Nav)

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Androctonus crassicauda (Arabian fat-tailed scorpion)
Neurotoxin Ion channel impairing toxin Voltage-gated sodium channel impairing toxin
Binds to sodium channels (Nav) and affects the channel activation process..
Toxin b subunit alpha
scorpion
Evidence at protein level
Direct protein sequencing Ion channel impairing toxin Neurotoxin Secreted Toxin Voltage-gated sodium channel impairing toxin
TISSUE SPECIFICITY: Expressed by the venom gland.
Additional Detail Fields 6 fields
Direct protein sequencing Ion channel impairing toxin Neurotoxin Secreted Toxin Voltage-gated sodium channel impairing toxin
Neurotoxin Ion channel impairing toxin Voltage-gated sodium channel impairing toxin
Evidence at protein level
Toxin b subunit alpha
TISSUE SPECIFICITY: Expressed by the venom gland.
scorpion