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Peptide record

TPDB28658

Neurotoxin Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB28658
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
CCNWPCSFGCIPCCY
Physicochemical Analysis
C72H99N17O19S6
ARDEQHLKMTV
C
1699.04
4.94
0
0
4
-0
-4.21
0.813
26.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7365
433.48
9
Residue Composition
number
0
A
0
R
1
N
0
D
6
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
1
F
2
P
1
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 6 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 1 P: 2 S: 1 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
15
C72H99N17O19S6
1699.04
4.94
-0
-4.21
0.813
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target (Probable). Possibly targets ion channels (Probable). In vivo, intraperitoneal injection into fish provokes paralysis after 5 minutes (PubMed:20570703). {ECO:0000269|PubMed:20570703, ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus parius (Cone snail)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target (Probable). Possibly targets ion channels (Probable).
Conotoxin pr3a
cone snail
Conotoxin M superfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:20570703}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin M superfamily
Conotoxin pr3a
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:20570703}.
cone snail