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Peptide record

TPDB28214

Neurotoxin Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB28214
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
AFVKGSAQRVAHGY
Physicochemical Analysis
C67H103N21O18
NDCEILMPTW
A
1490.68
10.42
3
0
7
+2
1.05
-0.100
62.86
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
99.95
3
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
0
E
1
Q
2
G
1
H
0
I
0
L
1
K
0
M
1
F
0
P
1
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
14
C67H103N21O18
1490.68
10.42
+2
1.05
-0.100
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Is a potent and mollusk specific excitatory peptide. Most potent excitatory effect are observed on the buccal mass. It interacts with non-cholinergic receptors. As this peptide is a major component of the venom, it may play an important role in prey capture.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus planorbis (Planorbis cone)
Neurotoxin
Is a potent and mollusk specific excitatory peptide. Most potent excitatory effect are observed on the buccal mass.
Conomap-Vt (Conp-Vt)
cone snail
Evidence at protein level
Amidation D-amino acid Direct protein sequencing Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:16797543}.
Additional Detail Fields 6 fields
Amidation D-amino acid Direct protein sequencing Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Conomap-Vt (Conp-Vt)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:16797543}.
cone snail