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Peptide record

TPDB28189

Neurotoxin Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB28189
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
AFCKYNGEQCTSDGQCCNGRCRTAFMGKICMG
Physicochemical Analysis
C139H220N44O45S8
HLPWV
C
3484.02
8.02
4
2
8
+2
3.56
-0.337
18.44
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1865
53.53
14
Residue Composition
number
2
A
2
R
2
N
1
D
6
C
1
E
2
Q
5
G
0
H
1
I
0
L
2
K
2
M
2
F
0
P
1
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 1 C: 6 E: 1 Q: 2 G: 5 H: 0 I: 1 L: 0 K: 2 M: 2 F: 2 P: 0 S: 1 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
32
C139H220N44O45S8
3484.02
8.02
+2
3.56
-0.337
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: May act as a neurotoxin. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Phoneutria keyserlingi (Brazilian wandering spider) (Ctenus keyserlingii)
Neurotoxin
May act as a neurotoxin..
U3-ctenitoxin-Pk1a (U3-CNTX-Pk1a) (Neurotoxin PKTx21C2) [Cleaved into: Neurotoxin PKTx21C2 variant Ala-1 Del]
spider
Neurotoxin 17 (21C2) family
Evidence at protein level
Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:16278100, ECO:0000305|Ref.2}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 17 (21C2) family
U3-ctenitoxin-Pk1a (U3-CNTX-Pk1a) (Neurotoxin PKTx21C2) [Cleaved into: Neurotoxin PKTx21C2 variant Ala-1 Del]
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:16278100, ECO:0000305|Ref.2}.
spider