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Peptide record

TPDB28165

Neurotoxin Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB28165
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
AELTSCFPVDHECDGGASNCNCCGDDVYCA
Physicochemical Analysis
C122H180N34O49S6
RQIKMW
C
3099.33
3.31
1
6
8
-6
7.20
-0.073
42.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1865
60.17
12
Residue Composition
number
3
A
0
R
2
N
4
D
6
C
2
E
0
Q
3
G
1
H
0
I
1
L
0
K
0
M
1
F
1
P
2
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 4 C: 6 E: 2 Q: 0 G: 3 H: 1 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 2 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
30
C122H180N34O49S6
3099.33
3.31
-6
7.20
-0.073
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Lethal neurotoxin. Causes spastic paralysis and death in mice in 4-6 minutes after intracerebroventricular injection at dose levels of 1.5 ug per mouse. {ECO:0000269|Ref.2}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Phoneutria keyserlingi (Brazilian wandering spider) (Ctenus keyserlingii)
Neurotoxin
Lethal neurotoxin. Causes spastic paralysis and death in mice in 4-6 minutes after intracerebroventricular injection at dose levels of 1.5 ug per mouse..
U5-ctenitoxin-Pk1b (U5-CNTX-Pk1b) (Neurotoxin PKTx16C1) (Neurotoxin PKTx1B)
spider
Neurotoxin 04 (omega-agtx) family, 02 (Tx1) subfamily
Evidence at protein level
Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|PubMed:16278100}.
Additional Detail Fields 7 fields
Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 04 (omega-agtx) family, 02 (Tx1) subfamily
U5-ctenitoxin-Pk1b (U5-CNTX-Pk1b) (Neurotoxin PKTx16C1) (Neurotoxin PKTx1B)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000269|PubMed:16278100}.
spider