TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB28156

Activity

Toxicity

Activity_category_statistics

Toxicity and safety peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 108-aa standard natural toxicity peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

AFAGILADADIAAALAACKAEGSFKHGEYFAKIGLKGKSAADIKKVFGIIDQDKSDFVEEDELKLFLQNFSAGARALTDAETATFLKAGDSDGDGKIGVDEFAAMVKG

FASTA

>TPDB28156|Toxicity|length=108
AFAGILADADIAAALAACKAEGSFKHGEYFAKIGLKGKSAADIKKVFGIIDQDKSDFVEEDELKLFLQNFSAGARALTDAETATFLKAGDSDGDGKIGVDEFAAMVKG

Formula C503H788N128O159S2

Absent Amino Acids PW

Common Amino Acids A

Mass 11236.67

PI 4.47

Basic Residues 14

Acidic Residues 19

Hydrophobic Residues 51

Net Charge -6

Boman Index 23.80

Hydrophobicity 0.022

Aliphatic Index 84.35

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1490

Absorbance 280nm 13.26

Polar Residues 13

number

21

A

1

R

1

N

12

D

1

C

7

E

2

Q

12

G

1

H

7

I

8

L

12

K

1

M

9

F

0

P

5

S

3

T

0

W

1

Y

4

V

Amino Acid Distribution

A: 21 R: 1 N: 1 D: 12 C: 1 E: 7 Q: 2 G: 12 H: 1 I: 7 L: 8 K: 12 M: 1 F: 9 P: 0 S: 5 T: 3 W: 0 Y: 1 V: 4

Length

108

Formula

C503H788N128O159S2

Mass

11236.67

PI

4.47

Net Charge

-6

Boman Index

23.80

Hydrophobicity

0.022

Evidence 1 Activity

Source & Reference

Database Source NA