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Peptide record

TPDB27769

Neurotoxin Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB27769
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia pep-lab ToxinPred 3.0
standard
No
A 32-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, pep-lab, and other sources, with an available 3D structural model.
Sequence
WLGCARVKEACGPWEWPCCSGLKCDGSECHPQ
Physicochemical Analysis
C151H223N43O44S6
NIMFTY
C
3537.05
5.42
4
4
8
-1
4.89
-0.416
39.69
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16875
477.09
9
Residue Composition
number
2
A
1
R
0
N
1
D
6
C
3
E
1
Q
4
G
1
H
0
I
2
L
2
K
0
M
0
F
3
P
2
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 1 C: 6 E: 3 Q: 1 G: 4 H: 1 I: 0 L: 2 K: 2 M: 0 F: 0 P: 3 S: 2 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
32
C151H223N43O44S6
3537.05
5.42
-1
4.89
-0.416
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Is both paralytic and lethal, when injected into lepidopteran larvae. Is a slower acting toxin, being lethal at 24 hours, but not paralytic at 1 hour post-injection.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Apomastus schlingeri (Trap-door spider) (Aptostichus schlingeri)
Neurotoxin
Is both paralytic and lethal, when injected into lepidopteran larvae. Is a slower acting toxin, being lethal at 24 hours, but not paralytic at 1 hour post-injection.
U3-cyrtautoxin-As1a (U3-CUTX-As1a) (Aptotoxin VII) (Aptotoxin-7) (Paralytic peptide VII) (PP VII)
spider
Neurotoxin 14 (magi-1) family
Evidence at protein level
3D-structure Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland.
Additional Detail Fields 7 fields
3D-structure Direct protein sequencing Disulfide bond Knottin Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Neurotoxin 14 (magi-1) family
U3-cyrtautoxin-As1a (U3-CUTX-As1a) (Aptotoxin VII) (Aptotoxin-7) (Paralytic peptide VII) (PP VII)
TISSUE SPECIFICITY: Expressed by the venom gland.
spider