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Peptide record

TPDB27575

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB27575
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AFP-GFuse
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and AFP-GFuse, with an available 3D structural model.
Sequence
YVSPVAIVKGLNIPL
Physicochemical Analysis
C76H127N17O19
RDCEQHMFTW
V
1582.95
9.74
1
0
9
+1
-0.19
1.193
168.67
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
94.13
3
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
1
K
0
M
0
F
2
P
1
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 1 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
15
C76H127N17O19
1582.95
9.74
+1
-0.19
1.193
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.94 µM

Target

M. luteus

Source & Reference

NA

Other

active against Gram-positive bacteria M. luteus (MIC 1.94 uM), Filamentous fungus A. niger (MIC 31.01 uM), yeast C. neoformans VNI WM 148 (MIC 22.75 uM
Evidence 2 Activity

Activity

MIC
Antibacterial
31.01 µM

Target

A. niger

Source & Reference

NA

Other

active against Gram-positive bacteria M. luteus (MIC 1.94 uM), Filamentous fungus A. niger (MIC 31.01 uM), yeast C. neoformans VNI WM 148 (MIC 22.75 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
22.75 µM

Target

C. neoformans VNI WM 148

Source & Reference

NA

Other

itive bacteria M. luteus (MIC 1.94 uM), Filamentous fungus A. niger (MIC 31.01 uM), yeast C. neoformans VNI WM 148 (MIC 22.75 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
1.94 µM

Target

M. luteus

Source & Reference

NA

Other

active against Gram-positive bacteria M. luteus (MIC 1.94 uM), Filamentous fungus A. niger (MIC 31.01 uM), yeast C. neoformans VNI WM 148 (MIC 22.75 uM
Evidence 5 Activity

Activity

MIC
Antifungal
31.01 µM

Target

A. niger

Source & Reference

NA

Other

active against Gram-positive bacteria M. luteus (MIC 1.94 uM), Filamentous fungus A. niger (MIC 31.01 uM), yeast C. neoformans VNI WM 148 (MIC 22.75 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
22.75 µM

Target

C. neoformans VNI WM 148

Source & Reference

NA

Other

itive bacteria M. luteus (MIC 1.94 uM), Filamentous fungus A. niger (MIC 31.01 uM), yeast C. neoformans VNI WM 148 (MIC 22.75 uM).
Evidence 7 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ovipin: a new antimicrobial peptide from chicken eggs Gallus gallus | bioRxiv | 2022
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Mining the UniProtKB/Swiss-Prot database for antimicrobial peptides | bioRxiv | 2024