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Peptide record

TPDB27474

Antibacterial Antifungal standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB27474
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 65-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
YPLDQVEEQDEHQVAHIRVRRVTCDLLSAEAKGVKVNHAACAAHCLLKRKRGGYCNKRRICVCRN
Physicochemical Analysis
C313H522N108O90S6
MFW
R
7430.62
9.20
17
7
23
+6
23.35
-0.549
84.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
3355
45.15
16
Residue Composition
number
7
A
8
R
3
N
3
D
6
C
4
E
3
Q
3
G
4
H
2
I
5
L
5
K
0
M
0
F
1
P
1
S
1
T
0
W
2
Y
7
V
Amino Acid Distribution
A: 7 R: 8 N: 3 D: 3 C: 6 E: 4 Q: 3 G: 3 H: 4 I: 2 L: 5 K: 5 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 2 V: 7
Chemical Descriptors
65
C313H522N108O90S6
7430.62
9.20
+6
23.35
-0.549
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16-64 µg/mL

Target

Staphylococcus epidermidis 9142

Source & Reference

NA

Other

USA300, USA400, RN4220, Newman, and clinical isolates including BF1,BF5, BF7 to BF11 and S. epidermidis 9142 (MIC 16-64 ug/ml). Of the 23 AMPs tested, only this peptide is effective against S. pneumoniae D39 ( Lindha
Evidence 2 Activity

Activity

MIC
Antifungal
16-64 µg/mL

Target

Staphylococcus epidermidis 9142

Source & Reference

Antifungipept

Other

USA300, USA400, RN4220, Newman, and clinical isolates including BF1,BF5, BF7 to BF11 and S. epidermidis 9142 (MIC 16-64 ug/ml). Of the 23 AMPs tested, only this peptide is effective against S. pneumoniae D39 ( Lindha