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Peptide record

TPDB27448

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB27448
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
YKVTMTCSAS
Physicochemical Analysis
C45H75N11O16S2
RNDEQGHILFPW
ST
1090.27
8.88
1
0
4
+1
0.02
0.220
39.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
136.66
6
Residue Composition
number
1
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
0
F
0
P
2
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
10
C45H75N11O16S2
1090.27
8.88
+1
0.02
0.220
Evidence Records 4 records
Evidence 1 Activity

Activity

<2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
<2% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 2 Activity

Activity

3.11% Killing
Toxicity
10 µM
Cytotoxic
3.11% Killing | 10 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 3 Activity

Activity

4.65% Killing
Toxicity
25 µM
Cytotoxic
4.65% Killing | 25 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021
Evidence 4 Activity

Activity

2.82% Killing
Toxicity
50 µM
Cytotoxic
2.82% Killing | 50 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Vitro and In Vivo Anti- Candida Activity and Structural Analysis of Killer Peptide (KP)-Derivatives. | J Fungi (Basel) | 2021