Back to search

Peptide record

TPDB27411

Antibacterial Antifungal Toxicity standard
77 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB27411
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 77-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
YFCESCRKIIQKLEDMVGPQPNEDTVTQAASQVCDKLKILRGLCKKIMRSFLRRISWDILTGKKPQAICVDIKICKE
Physicochemical Analysis
C389H653N109O110S8
H
K
8873.61
9.16
15
9
28
+6
20.49
-0.229
94.94
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
7365
83.00
20
Residue Composition
number
3
A
5
R
1
N
5
D
6
C
4
E
5
Q
3
G
0
H
9
I
6
L
10
K
2
M
2
F
3
P
4
S
3
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 3 R: 5 N: 1 D: 5 C: 6 E: 4 Q: 5 G: 3 H: 0 I: 9 L: 6 K: 10 M: 2 F: 2 P: 3 S: 4 T: 3 W: 1 Y: 1 V: 4
Chemical Descriptors
77
C389H653N109O110S8
8873.61
9.16
+6
20.49
-0.229
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
170 µM
Hemolytic Cytotoxic
0% Hemolysis | 170 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity. | EMBO J | 1995