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Peptide record

TPDB27387

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB27387
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WLKKLKKKLKKLKKK
Physicochemical Analysis
C95H176N26O16
ARNDCEQGHIMFPSTYV
K
1938.61
11.46
10
0
5
+10
5.81
-1.647
104.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
283.71
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
10
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 10 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C95H176N26O16
1938.61
11.46
+10
5.81
-1.647
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designing double-site lipidated peptide amphiphiles as potent antimicrobial biomaterials to combat multidrug-resistant bacteria. | Front Microbiol | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Intestinal Porcine Epithelial Cells IPEC-J2

Target

Intestinal Porcine Epithelial Cells IPEC-J2

Source & Reference

NA
DBAASP
Designing double-site lipidated peptide amphiphiles as potent antimicrobial biomaterials to combat multidrug-resistant bacteria. | Front Microbiol | 2022
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Designing double-site lipidated peptide amphiphiles as potent antimicrobial biomaterials to combat multidrug-resistant bacteria. | Front Microbiol | 2022