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Peptide record

TPDB27386

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB27386
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WLKKALKIGAKLLPSVVKLFKGSGQ
Physicochemical Analysis
C130H221N33O29
RNDCEHMTY
K
2710.39
11.21
6
0
12
+6
0.97
0.244
124.80
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
202.92
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
5
L
6
K
0
M
1
F
1
P
2
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 5 K: 6 M: 0 F: 1 P: 1 S: 2 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
25
C130H221N33O29
2710.39
11.21
+6
0.97
0.244
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
10% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides. | Biochemistry | 2021