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Peptide record

TPDB27369

Antibacterial Toxicity modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB27369
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 17-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XIKKXLKSAKKFVKAFK
Physicochemical Analysis
C86H150N22O17
RNDCEQGHMPTWY
K
1764.27
11.29
7
0
7
+7
3.66
-0.376
74.71
Mammalian: Yeast: E.coli:
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
7
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 7 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C86H150N22O17
1764.27
11.29
+7
3.66
-0.376
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
50% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence. | Molecules | 2021
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
50% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence. | Molecules | 2021
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
0.78 µM
Hemolytic Cytotoxic
50% Hemolysis | 0.78 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence. | Molecules | 2021