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Peptide record

TPDB27346

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
2 amino acids
Basic Information
3D PDB MODEL
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TPDB27346
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 2-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
XH
Physicochemical Analysis
C6H9N3O2
ARNDCEQGILKMFPSTWYV
H
155.16
7.85
1
0
0
+0
0.96
-1.600
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C6H9N3O2
155.16
7.85
+0
0.96
-1.600
Evidence Records 5 records
Evidence 1 Activity

Activity

IC50
Toxicity
>50 µg/mL
Cytotoxic
IC50 | >50 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach. | Int J Mol Sci | 2021
Evidence 2 Activity

Activity

IC50
Toxicity
>50 µg/mL
Cytotoxic
IC50 | >50 | µg/mL | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach. | Int J Mol Sci | 2021
Evidence 3 Activity

Activity

IC50
Toxicity
25 µg/mL
Cytotoxic
IC50 | 25 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach. | Int J Mol Sci | 2021
Evidence 4 Activity

Activity

IC50
Toxicity
12.5 µg/mL
Cytotoxic
IC50 | 12.5 | µg/mL | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach. | Int J Mol Sci | 2021
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Bioorg Med Chem Lett. 2012 Jun 15 22(12):3866-9.