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Peptide record

TPDB27338

Antibacterial Antifungal Toxicity modified_plain modified
38 amino acids
Basic Information
3D PDB MODEL
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TPDB27338
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 38-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
XGVSCLRNGGFCIPIRCPGHTRQIGTCFGPRVKCCRKW
Physicochemical Analysis
C176H285N59O43S6
ADEMY
CG
4107.93
9.97
8
0
9
+7
2.91
-0.118
56.32
Mammalian: Yeast: E.coli:
5875
143.02
11
Residue Composition
number
0
A
5
R
1
N
0
D
6
C
0
E
1
Q
6
G
1
H
3
I
1
L
2
K
0
M
2
F
3
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 6 E: 0 Q: 1 G: 6 H: 1 I: 3 L: 1 K: 2 M: 0 F: 2 P: 3 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
38
C176H285N59O43S6
4107.93
9.97
+7
2.91
-0.118
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
10% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Artificial beta-defensin based on a minimal defensin template. | Biochem J | 2009
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Artificial beta-defensin based on a minimal defensin template. | Biochem J | 2009