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Peptide record

TPDB27332

Antibacterial Toxicity modified_plain modified
22 amino acids
Basic Information
3D PDB MODEL
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TPDB27332
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 22-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XGPLGVRGKRLWDIVRRWVGWL
Physicochemical Analysis
C119H187N37O24
ANCEQHMFSTY
RG
2520.03
12.41
5
1
10
+4
-1.38
-0.127
110.45
Mammalian: Yeast: E.coli:
16500
654.75
0
Residue Composition
number
0
A
4
R
0
N
1
D
0
C
0
E
0
Q
4
G
0
H
1
I
3
L
1
K
0
M
0
F
1
P
0
S
0
T
3
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 3 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 3 Y: 0 V: 3
Chemical Descriptors
22
C119H187N37O24
2520.03
12.41
+4
-1.38
-0.127
Evidence Records 2 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility | J Control Release | 2021
Evidence 2 Activity

Activity

60% Cytotoxicity
Toxicity
125 µg/mL
Cytotoxic
60% Cytotoxicity | 125 | µg/mL | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility | J Control Release | 2021