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Peptide record

TPDB27322

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB27322
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
XGLXGGLXGIL
Physicochemical Analysis
C32H58N8O9
ARNDCEQHKMFPSTWYV
G
698.86
6.02
0
0
4
-0
-1.95
1.300
141.82
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C32H58N8O9
698.86
6.02
-0
-1.95
1.300
Evidence Records 6 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
5% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human lymphocytes

Target

Human lymphocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 4 Activity

Activity

2% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
2% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Trichogin GA IV: an antibacterial and protease-resistant peptide. | J Pept Sci | 2009
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta. 2015 Jan 1848(1 Pt A):134-45.
Evidence 6 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2016 Apr 4 6:24000.