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Peptide record

TPDB27290

Antibacterial Antifungal Toxicity modified_plain modified
8 amino acids
Basic Information
3D PDB MODEL
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TPDB27290
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 8-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
XFFLRRIF
Physicochemical Analysis
C51H75N13O8
ANDCEQGHKMPSTWYV
F
998.24
12.40
2
0
5
+2
-2.64
0.962
97.50
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C51H75N13O8
998.24
12.40
+2
-2.64
0.962
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
90 µM
Hemolytic Cytotoxic
50% Hemolysis | 90 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity | ACS Chem Biol | 2015