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Peptide record

TPDB27271

Antibacterial Anticancer Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB27271
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XCRRLCYRNRCVTYCRGR
Physicochemical Analysis
C87H148N36O22S4
ADEQHIKMFPSW
R
2178.60
10.26
6
0
4
+6
2.10
-0.900
37.78
Mammalian: Yeast: E.coli:
3230
148.26
8
Residue Composition
number
0
A
6
R
1
N
0
D
4
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 4 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
18
C87H148N36O22S4
2178.60
10.26
+6
2.10
-0.900
Evidence Records 5 records
Evidence 1 Activity

Activity

10% Killing
Toxicity
75 µg/mL
Cytotoxic
10% Killing | 75 | µg/mL | target cell: Human neonatal skin fbroblasts NFF

Target

Human neonatal skin fbroblasts NFF

Source & Reference

NA
DBAASP
Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. | Sci Rep | 2018
Evidence 2 Activity

Activity

100% Killing
Toxicity
100-200 µg/mL
Cytotoxic
100% Killing | 100-200 | µg/mL | target cell: Human neonatal skin fbroblasts NFF

Target

Human neonatal skin fbroblasts NFF

Source & Reference

NA
DBAASP
Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. | Sci Rep | 2018
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. | Sci Rep | 2018
Evidence 4 Activity

Activity

18% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation. | Sci Rep | 2018
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2018 Aug 1 8(1):11519.