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Peptide record

TPDB27260

Antibacterial Toxicity modified_plain modified
93 amino acids
Basic Information
3D PDB MODEL
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TPDB27260
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 93-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XAQALLPIASYAGLTVSAPVFAALVTVYGAYALYRYNIRRRENSYQRIRSDHDSHSCANNRGWCRPTCFSHEYTDWFNNDVCGSYRCCRPGRR
Physicochemical Analysis
C462H696N144O133S6
KM
R
10587.85
9.07
15
6
36
+6
7.56
-0.511
59.89
Mammalian: Yeast: E.coli:
23295
220.02
34
Residue Composition
number
10
A
12
R
6
N
4
D
6
C
2
E
2
Q
5
G
3
H
3
I
5
L
0
K
0
M
3
F
4
P
8
S
4
T
2
W
8
Y
5
V
Amino Acid Distribution
A: 10 R: 12 N: 6 D: 4 C: 6 E: 2 Q: 2 G: 5 H: 3 I: 3 L: 5 K: 0 M: 0 F: 3 P: 4 S: 8 T: 4 W: 2 Y: 8 V: 5
Chemical Descriptors
93
C462H696N144O133S6
10587.85
9.07
+6
7.56
-0.511
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human bronchial epithelial cells

Target

Human bronchial epithelial cells

Source & Reference

NA
DBAASP
The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets | MBio | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets | MBio | 2019