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Peptide record

TPDB27259

Antibacterial Toxicity modified_plain modified
42 amino acids
Basic Information
3D PDB MODEL
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TPDB27259
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 42-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XAQALLPIASYAGLTVSAPVFAALVTVYGAYALYRYNIRRRE
Physicochemical Analysis
C209H327N55O55
DCHKMW
A
4490.23
10.00
4
1
26
+3
-2.78
0.519
114.05
Mammalian: Yeast: E.coli:
7450
165.92
11
Residue Composition
number
9
A
4
R
1
N
0
D
0
C
1
E
1
Q
2
G
0
H
2
I
5
L
0
K
0
M
1
F
2
P
2
S
2
T
0
W
5
Y
4
V
Amino Acid Distribution
A: 9 R: 4 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 2 L: 5 K: 0 M: 0 F: 1 P: 2 S: 2 T: 2 W: 0 Y: 5 V: 4
Chemical Descriptors
42
C209H327N55O55
4490.23
10.00
+3
-2.78
0.519
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human bronchial epithelial cells

Target

Human bronchial epithelial cells

Source & Reference

NA
DBAASP
The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets | MBio | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets | MBio | 2019