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Peptide record

TPDB27244

Antibacterial Anticancer Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB27244
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WVILSKKIKRKKKENSDHQTKFSKKVKTKR
Physicochemical Analysis
C167H290N52O42
ACGMPY
K
3698.46
11.42
14
2
7
+11
14.37
-1.660
58.33
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
148.71
7
Residue Composition
number
0
A
2
R
1
N
1
D
0
C
1
E
1
Q
0
G
1
H
2
I
1
L
11
K
0
M
1
F
0
P
3
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 2 L: 1 K: 11 M: 0 F: 1 P: 0 S: 3 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
30
C167H290N52O42
3698.46
11.42
+11
14.37
-1.660
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

B. subtilis ATCC 6051

Source & Reference

NA

Other

Active against B. subtilis ATCC 6051 (MIC 16 ug/ml), E.coli KCCM 11234 (MIC 256 ug/ml), P.aeruginosa ATCC 9027 (MIC 256 ug/ml), S. aureus KCC
Evidence 2 Activity

Activity

MIC
Antibacterial
256 µg/mL

Target

E.coli KCCM 11234

Source & Reference

NA

Other

Active against B. subtilis ATCC 6051 (MIC 16 ug/ml), E.coli KCCM 11234 (MIC 256 ug/ml), P.aeruginosa ATCC 9027 (MIC 256 ug/ml), S. aureus KCCM 11335 (MIC 32 ug/ml), and S.epide
Evidence 3 Activity

Activity

MIC
Antibacterial
256 µg/mL

Target

P.aeruginosa ATCC 9027

Source & Reference

NA

Other

Active against B. subtilis ATCC 6051 (MIC 16 ug/ml), E.coli KCCM 11234 (MIC 256 ug/ml), P.aeruginosa ATCC 9027 (MIC 256 ug/ml), S. aureus KCCM 11335 (MIC 32 ug/ml), and S.epidermidis ATCC 12228 (MIC 256 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Staphylococcus aureus KCCM 11335

Source & Reference

NA

Other

MIC 16 ug/ml), E.coli KCCM 11234 (MIC 256 ug/ml), P.aeruginosa ATCC 9027 (MIC 256 ug/ml), S. aureus KCCM 11335 (MIC 32 ug/ml), and S.epidermidis ATCC 12228 (MIC 256 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
256 µg/mL

Target

S.epidermidis ATCC 12228

Source & Reference

NA

Other

ug/ml), P.aeruginosa ATCC 9027 (MIC 256 ug/ml), S. aureus KCCM 11335 (MIC 32 ug/ml), and S.epidermidis ATCC 12228 (MIC 256 ug/ml).
Evidence 6 Activity

Activity

IC50
Toxicity
>256 µg/mL
Cytotoxic
IC50 | >256 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Identifying novel antimicrobial peptides from venom gland of spider Pardosa astrigera by deep multi-task learning | Front Microbiol | 2022
Evidence 7 Activity

Activity

IC50
Toxicity
>256 µg/mL
Cytotoxic
IC50 | >256 | µg/mL | target cell: Human normal astrocytes

Target

Human normal astrocytes

Source & Reference

NA
DBAASP
Identifying novel antimicrobial peptides from venom gland of spider Pardosa astrigera by deep multi-task learning | Front Microbiol | 2022
Evidence 8 Activity

Activity

IC50
Toxicity
>256 µg/mL
Cytotoxic
IC50 | >256 | µg/mL | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Identifying novel antimicrobial peptides from venom gland of spider Pardosa astrigera by deep multi-task learning | Front Microbiol | 2022
Evidence 9 Activity

Activity

<3% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
<3% Hemolysis | 512 | µg/mL | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Identifying novel antimicrobial peptides from venom gland of spider Pardosa astrigera by deep multi-task learning | Front Microbiol | 2022