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Peptide record

TPDB27211

Antibacterial Anticancer Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB27211
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XXXXXXXXXXX
Physicochemical Analysis
ARNDCEQGHILKMFPSTWYV
18.02
6.02
0
0
0
-0
0.00
0.000
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
18.02
6.02
-0
0.00
0.000
Evidence Records 9 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
62 µM
Cytotoxic
50% Cell death | 62 | µM | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis. | Antimicrob Agents Chemother | 2011
Evidence 2 Activity

Activity

LC50
Toxicity
24 µM
Cytotoxic
LC50 | 24 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 3 Activity

Activity

LC50
Toxicity
19 µM
Cytotoxic
LC50 | 19 | µM | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 4 Activity

Activity

10% Hemolysis
Toxicity
103 µM
Hemolytic Cytotoxic
10% Hemolysis | 103 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 5 Activity

Activity

IC50
Toxicity
>200 µM
Cytotoxic
IC50 | >200 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Antimicrobial Peptide-Peptoid Hybrids with and without Membrane Disruption. | ACS Infect Dis | 2023
Evidence 6 Activity

Activity

5% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptide-Peptoid Hybrids with and without Membrane Disruption. | ACS Infect Dis | 2023
Evidence 7 Activity

Activity

LC50
Toxicity
>100 µM
Cytotoxic
LC50 | >100 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 8 Activity

Activity

LC50
Toxicity
>100 µM
Cytotoxic
LC50 | >100 | µM | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 9 Activity

Activity

10% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
10% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014