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Peptide record

TPDB27210

Antibacterial Anticancer Toxicity modified_plain modified
9 amino acids
Basic Information
3D PDB MODEL
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TPDB27210
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 9-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XXXXXXXXX
Physicochemical Analysis
ARNDCEQGHILKMFPSTWYV
18.02
6.02
0
0
0
-0
0.00
0.000
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
18.02
6.02
-0
0.00
0.000
Evidence Records 18 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
<1% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial mechanisms of GN-2 derived peptides and peptoids against Escherichia coli. | Biopolymers | 2019
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 3 Activity

Activity

<10% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 4 Activity

Activity

10% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 5 Activity

Activity

10% Hemolysis
Toxicity
4 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 4 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 6 Activity

Activity

10% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 7 Activity

Activity

10% Hemolysis
Toxicity
4-8 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 4-8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 8 Activity

Activity

10% Hemolysis
Toxicity
119.5 µM
Hemolytic Cytotoxic
10% Hemolysis | 119.5 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids | Bioorg Med Chem Lett | 2018
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids | Bioorg Med Chem Lett | 2018
Evidence 10 Activity

Activity

IC50
Toxicity
40 µM
Cytotoxic
IC50 | 40 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Effect of side chain hydrophobicity and cationic charge on antimicrobial activity and cytotoxicity of helical peptoids | Bioorg Med Chem Lett | 2018
Evidence 11 Activity

Activity

LC50
Toxicity
32 µM
Cytotoxic
LC50 | 32 | µM | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 12 Activity

Activity

10% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
10% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity | PLoS One | 2014
Evidence 13 Activity

Activity

50% Hemolysis
Toxicity
>400 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >400 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species | Pharmaceuticals (Basel) | 2015
Evidence 14 Activity

Activity

50% Hemolysis
Toxicity
161±40 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 161±40 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species | Pharmaceuticals (Basel) | 2015
Evidence 15 Activity

Activity

50% Hemolysis
Toxicity
77±16 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 77±16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species | Pharmaceuticals (Basel) | 2015
Evidence 16 Activity

Activity

50% Hemolysis
Toxicity
341±34 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 341±34 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species | Pharmaceuticals (Basel) | 2015
Evidence 17 Activity

Activity

50% Hemolysis
Toxicity
15±7 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 15±7 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species | Pharmaceuticals (Basel) | 2015
Evidence 18 Activity

Activity

<10% Hemolysis
Toxicity
5000 µM
Hemolytic Cytotoxic
<10% Hemolysis | 5000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A study on antimicrobial activity of lysine-like peptoids for the development of new antimicrobials | Arch Microbiol | 2025