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Peptide record

TPDB27207

Antibacterial Anticancer Toxicity modified_plain modified
8 amino acids
Basic Information
3D PDB MODEL
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TPDB27207
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 8-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XXXXXXXX
Physicochemical Analysis
ARNDCEQGHILKMFPSTWYV
18.02
6.02
0
0
0
-0
0.00
0.000
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
18.02
6.02
-0
0.00
0.000
Evidence Records 11 records
Evidence 1 Activity

Activity

24% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
24% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues. | Molecules | 2019
Evidence 2 Activity

Activity

69% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
69% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues. | Molecules | 2019
Evidence 3 Activity

Activity

87% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
87% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues. | Molecules | 2019
Evidence 4 Activity

Activity

16% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
16% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues. | Molecules | 2019
Evidence 5 Activity

Activity

5% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
5% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues. | Molecules | 2019
Evidence 6 Activity

Activity

10% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 7 Activity

Activity

10% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 8 Activity

Activity

10% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of novel peptoids that mimic the structure of antimicrobial peptides. | Antimicrob Agents Chemother | 2015
Evidence 9 Activity

Activity

10% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents | ChemMedChem | 2012
Evidence 10 Activity

Activity

50% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A comparison of linear and cyclic peptoid oligomers as potent antimicrobial agents | ChemMedChem | 2012
Evidence 11 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Mol Biosyst. 2012 Oct 8(10):2626-8.