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Peptide record

TPDB27188

Antibacterial Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB27188
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XXXRIRIRWIIR
Physicochemical Analysis
C59H104N22O10
ANDCEQGHLKMFPSTYV
RI
1281.62
12.88
4
0
5
+4
0.15
-0.075
130.00
Mammalian: Yeast: E.coli:
5500
429.15
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
4
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C59H104N22O10
1281.62
12.88
+4
0.15
-0.075
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
132.0 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 132.0 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
73 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 73 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
35 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 35 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
28 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 28 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020