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Peptide record

TPDB27175

Antibacterial Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB27175
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XXXKRRVRWIIW
Physicochemical Analysis
C63H101N21O10
ANDCEQGHLMFPSTY
R
1312.63
12.71
4
0
5
+4
-0.83
-0.500
89.17
Mammalian: Yeast: E.coli:
11000
838.01
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
12
C63H101N21O10
1312.63
12.71
+4
-0.83
-0.500
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
38 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 38 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The effect of lipidation and glycosylation on short cationic antimicrobial peptides. | Biochim Biophys Acta | 2020