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Peptide record

TPDB27167

Antibacterial Anticancer Antifungal Antiviral Toxicity modified_plain modified
3 amino acids
Basic Information
3D PDB MODEL
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TPDB27167
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 3-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
XXX
Physicochemical Analysis
ARNDCEQGHILKMFPSTWYV
18.02
6.02
0
0
0
-0
0.00
0.000
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
18.02
6.02
-0
0.00
0.000
Evidence Records 8 records
Evidence 1 Activity

Activity

IC50
Toxicity
25 µg/mL
Cytotoxic
IC50 | 25 | µg/mL | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Two novel hepatocellular carcinoma cycle inhibitory cyclodepsipeptides from a hydrothermal vent crab-associated fungus Aspergillus clavatus C2WU. | Mar Drugs | 2013
Evidence 2 Activity

Activity

10% Killing
Toxicity
40 µg/mL
Cytotoxic
10% Killing | 40 | µg/mL | target cell: Human fibroblasts

Target

Human fibroblasts

Source & Reference

NA
DBAASP
Zn-driven discovery of a hydrothermal vent fungal metabolite clavatustide C, and an experimental study of the anti-cancer mechanism of clavatustide B. | Mar Drugs | 2014
Evidence 3 Activity

Activity

IC50
Toxicity
>30 µM
Cytotoxic
IC50 | >30 | µM | target cell: Human gastric epithelial cells GES-1

Target

Human gastric epithelial cells GES-1

Source & Reference

NA
DBAASP
Antibacterial Cyclic Tripeptides from Antarctica-Sponge-Derived Fungus Aspergillus insulicola HDN151418. | Mar Drugs | 2020
Evidence 4 Activity

Activity

IC50
Toxicity
>30 µM
Cytotoxic
IC50 | >30 | µM | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Antibacterial Cyclic Tripeptides from Antarctica-Sponge-Derived Fungus Aspergillus insulicola HDN151418. | Mar Drugs | 2020
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
>1000 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >1000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Systematic study of non-natural short cationic lipopeptides as novel broad-spectrum antimicrobial agents. | Chem Biol Drug Des | 2013
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 1000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Systematic study of non-natural short cationic lipopeptides as novel broad-spectrum antimicrobial agents. | Chem Biol Drug Des | 2013
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
750 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 750 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Systematic study of non-natural short cationic lipopeptides as novel broad-spectrum antimicrobial agents. | Chem Biol Drug Des | 2013
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Systematic study of non-natural short cationic lipopeptides as novel broad-spectrum antimicrobial agents. | Chem Biol Drug Des | 2013