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Peptide record

TPDB27164

Antibacterial Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB27164
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XXWXXWXXWXX
Physicochemical Analysis
C33H32N6O4
ARNDCEQGHILKMFPSTYV
W
576.65
6.02
0
0
3
-0
-5.55
-0.245
0.00
Mammalian: Yeast: E.coli:
16500
2861.33
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
11
C33H32N6O4
576.65
6.02
-0
-5.55
-0.245
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
5% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides | Biochim Biophys Acta | 2009