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Peptide record

TPDB27161

Antibacterial Antiviral Toxicity modified_plain modified
4 amino acids
Basic Information
3D PDB MODEL
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TPDB27161
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0
modified_plain
Yes
A 4-aa modified multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia and dbAMP 3.0, with an available 3D structural model.
Modified, details unspecified
Sequence
XXWX
Physicochemical Analysis
C11H12N2O2
ARNDCEQGHILKMFPSTYV
W
204.23
6.02
0
0
1
-0
-1.85
-0.225
0.00
Mammalian: Yeast: E.coli:
5500
2693.06
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
4
C11H12N2O2
204.23
6.02
-0
-1.85
-0.225
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
41.38±0.04 µM
Cytotoxic
50% Cytotoxicity | 41.38±0.04 | µM | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Potent Influenza A Virus Entry Inhibitors Targeting a Conserved Region of Hemagglutinin | Biochem Pharmacol | 2017