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Peptide record

TPDB27137

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB27137
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
XXLFXXLLXYLXXF
Physicochemical Analysis
C51H73N7O9
ARNDCEQGHIKMPSTWV
L
928.18
5.94
0
0
7
-0
-5.44
1.393
111.43
Mammalian: Yeast: E.coli:
1490
160.53
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
2
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C51H73N7O9
928.18
5.94
-0
-5.44
1.393
Evidence Records 6 records
Evidence 1 Activity

Activity

17.41±1.82% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
17.41±1.82% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 2 Activity

Activity

41.03±1.38% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
41.03±1.38% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 3 Activity

Activity

100% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
100% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 4 Activity

Activity

31.17±0.85% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
31.17±0.85% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 5 Activity

Activity

66.51±3.14% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
66.51±3.14% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020
Evidence 6 Activity

Activity

74.68±1.34% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
74.68±1.34% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
D- and Unnatural Amino Acid Substituted Antimicrobial Peptides With Improved Proteolytic Resistance and Their Proteolytic Degradation Characteristics. | Front Microbiol | 2020