Back to search

Peptide record

TPDB27057

Antibacterial Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB27057
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XVRRFPWWWPFLRR
Physicochemical Analysis
C96H132N28O14
ANDCEQGHIKMSTY
R
1902.28
12.88
4
0
7
+4
-4.16
-0.736
48.57
Mammalian: Yeast: E.coli:
16500
867.38
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
2
F
2
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 2 P: 2 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
14
C96H132N28O14
1902.28
12.88
+4
-4.16
-0.736
Evidence Records 1 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
190 µM
Hemolytic Cytotoxic
7% Hemolysis | 190 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Comparison of Activity, Toxicity, and Conformation of Tritrpticin and Two TOAC-labeled Analogues. Effects on the Mechanism of Action. | Biochim Biophys Acta | 2019