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Peptide record

TPDB27055

Antibacterial Toxicity modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB27055
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 13-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XVQWFSKFLGRIL
Physicochemical Analysis
C74H112N18O15
ANDCEHMPTY
LF
1493.81
11.49
2
0
7
+2
-2.95
0.608
112.31
Mammalian: Yeast: E.coli:
5500
368.18
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C74H112N18O15
1493.81
11.49
+2
-2.95
0.608
Evidence Records 4 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
<10% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Modulating the Antimicrobial Activity of Temporin L Through Introduction of Fluorinated Phenylalanine | Int J Pept Res Ther | 2017
Evidence 2 Activity

Activity

80% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
80% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Modulating the Antimicrobial Activity of Temporin L Through Introduction of Fluorinated Phenylalanine | Int J Pept Res Ther | 2017
Evidence 3 Activity

Activity

100% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
100% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Modulating the Antimicrobial Activity of Temporin L Through Introduction of Fluorinated Phenylalanine | Int J Pept Res Ther | 2017
Evidence 4 Activity

Activity

100% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
100% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Modulating the Antimicrobial Activity of Temporin L Through Introduction of Fluorinated Phenylalanine | Int J Pept Res Ther | 2017