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Peptide record

TPDB26965

Antibacterial Toxicity modified_plain modified
4 amino acids
Basic Information
3D PDB MODEL
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TPDB26965
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 4-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XRXR
Physicochemical Analysis
C12H26N8O3
ANDCEQGHILKMFPSTWYV
R
330.39
12.40
2
0
0
+2
1.62
-2.250
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C12H26N8O3
330.39
12.40
+2
1.62
-2.250
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
22 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 22 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Self-assembly to function: design, synthesis, and broad spectrum antimicrobial properties of short hybrid E-vinylogous lipopeptides | J Med Chem | 2013
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
52 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 52 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Self-assembly to function: design, synthesis, and broad spectrum antimicrobial properties of short hybrid E-vinylogous lipopeptides | J Med Chem | 2013
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery of an ultra-short linear antibacterial tetrapeptide with anti-MRSA activity from a structure-activity relationship study. | Eur J Med Chem | 2015