Back to search

Peptide record

TPDB26945

Antibacterial Toxicity modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26945
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 21-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XRPDKPRPYLPRPRPPRPVRC
Physicochemical Analysis
C109H181N39O24S1
ANEQGHIMFSTW
P
2453.94
12.11
7
1
3
+6
9.01
-1.810
32.38
Mammalian: Yeast: E.coli:
1490
60.72
2
Residue Composition
number
0
A
6
R
0
N
1
D
1
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
8
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 8 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C109H181N39O24S1
2453.94
12.11
+6
9.01
-1.810
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
>125 µg/mL
Cytotoxic
IC50 | >125 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker. | Chem Sci | 2022
Evidence 2 Activity

Activity

IC50
Toxicity
>125 µg/mL
Cytotoxic
IC50 | >125 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP