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Peptide record

TPDB26910

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
2 amino acids
Basic Information
3D PDB MODEL
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TPDB26910
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 2-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XP
Physicochemical Analysis
C5H9N1O2
ARNDCEQGHILKMFSTWYV
P
115.13
6.02
0
0
0
-0
0.45
-0.800
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C5H9N1O2
115.13
6.02
-0
0.45
-0.800
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
Toxicity
>100 µM
Cytotoxic
IC50 | >100 | µM | target cell: Human normal breast epithelial cells fR-2

Target

Human normal breast epithelial cells fR-2

Source & Reference

NA
DBAASP
Cyclodipeptide c(Orn-Pro) Conjugate with 4-Ethylpiperic Acid Abrogates Cancer Cell Metastasis through Modulating MDM2. | Bioconjug Chem | 2018
Evidence 2 Activity

Activity

IC50
Toxicity
89.9±1.6 µM
Cytotoxic
IC50 | 89.9±1.6 | µM | target cell: Human normal breast epithelial cells fR-2

Target

Human normal breast epithelial cells fR-2

Source & Reference

NA
DBAASP
Cyclodipeptide c(Orn-Pro) Conjugate with 4-Ethylpiperic Acid Abrogates Cancer Cell Metastasis through Modulating MDM2. | Bioconjug Chem | 2018
Evidence 3 Activity

Activity

IC50
Toxicity
74.3±1.8 µM
Cytotoxic
IC50 | 74.3±1.8 | µM | target cell: Human normal breast epithelial cells fR-2

Target

Human normal breast epithelial cells fR-2

Source & Reference

NA
DBAASP
Cyclodipeptide c(Orn-Pro) Conjugate with 4-Ethylpiperic Acid Abrogates Cancer Cell Metastasis through Modulating MDM2. | Bioconjug Chem | 2018
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Bioorg Med Chem Lett. 2012 Jun 15 22(12):3866-9.