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Peptide record

TPDB26866

Antibacterial Antifungal Toxicity modified_plain modified
16 amino acids
Basic Information
3D PDB MODEL
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TPDB26866
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 16-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
XLWDVIRKVASVIGGL
Physicochemical Analysis
C76H128N20O19
NCEQHMFPTY
V
1625.97
10.09
2
1
9
+1
-0.37
1.038
158.12
Mammalian: Yeast: E.coli:
5500
338.26
1
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
2
I
2
L
1
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
16
C76H128N20O19
1625.97
10.09
+1
-0.37
1.038
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>32 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity. | Peptides | 2019
Evidence 2 Activity

Activity

IC50
Toxicity
30.90 µg/mL
Cytotoxic
IC50 | 30.90 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity. | Peptides | 2019