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Peptide record

TPDB26856

Antibacterial Anticancer Toxicity modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB26856
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 10-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XLLKRIKTLL
Physicochemical Analysis
C52H100N14O11
ANDCEQGHMFPSWYV
L
1097.45
11.64
3
0
5
+3
0.38
0.670
195.00
Mammalian: Yeast: E.coli:
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C52H100N14O11
1097.45
11.64
+3
0.38
0.670
Evidence Records 3 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Synthesis and anti-pseudomonal activity of new ß-Ala modified analogues of the antimicrobial peptide anoplin | Int J Med Microbiol | 2020
Evidence 2 Activity

Activity

15% Killing
Toxicity
256 µM
Cytotoxic
15% Killing | 256 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Synthesis and anti-pseudomonal activity of new ß-Ala modified analogues of the antimicrobial peptide anoplin | Int J Med Microbiol | 2020
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Horse erythrocytes : <5% Hemolysis=256µM | Cytotoxicity: HEK293T: 15% Hemolysis=256µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Int J Med Microbiol. 2020 Jul 310(5):151433.