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Peptide record

TPDB26834

Antibacterial Toxicity modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB26834
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 10-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XKLXGGLXGI
Physicochemical Analysis
C30H56N8O8
ARNDCEQHMFPSTWYV
G
656.82
10.10
1
0
3
+1
-0.41
0.700
117.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
2
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C30H56N8O8
656.82
10.10
+1
-0.41
0.700
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
4 µM
Hemolytic Cytotoxic
0% Hemolysis | 4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 2 Activity

Activity

8% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
8% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015
Evidence 3 Activity

Activity

35% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
35% Hemolysis | 16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The peculiar N- and (-termini of trichogin GA IV are needed for membrane interaction and human cell death induction at doses lacking antibiotic activity. | Biochim Biophys Acta | 2015