Back to search

Peptide record

TPDB26820

Antibacterial Antifungal Toxicity modified_plain modified
6 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB26820
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 6-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
XKKKKK
Physicochemical Analysis
C30H62N10O6
ARNDCEQGHILMFPSTWYV
K
658.89
11.12
5
0
0
+5
4.95
-3.250
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C30H62N10O6
658.89
11.12
+5
4.95
-3.250
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
40.4 µg/mL
Cytotoxic
50% Cell death | 40.4 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles. | ACS Appl Mater Interfaces | 2019
Evidence 2 Activity

Activity

50% Cell death
Toxicity
19.3 µg/mL
Cytotoxic
50% Cell death | 19.3 | µg/mL | target cell: Human Colon Epithelial Cells HCEC

Target

Human Colon Epithelial Cells HCEC

Source & Reference

NA
DBAASP
Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles. | ACS Appl Mater Interfaces | 2019
Evidence 3 Activity

Activity

50% Cell death
Toxicity
>32 µg/mL
Cytotoxic
50% Cell death | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles. | ACS Appl Mater Interfaces | 2019
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
8.1 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 8.1 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles. | ACS Appl Mater Interfaces | 2019