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Peptide record

TPDB26809

Antibacterial Toxicity modified_plain modified
4 amino acids
Basic Information
3D PDB MODEL
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TPDB26809
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 4-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XKGK
Physicochemical Analysis
C14H29N5O4
ARNDCEQHILMFPSTWYV
K
331.42
10.60
2
0
0
+2
1.99
-2.050
0.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C14H29N5O4
331.42
10.60
+2
1.99
-2.050
Evidence Records 12 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 50 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 2 Activity

Activity

1.10% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1.10% Hemolysis | 100 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 3 Activity

Activity

2.21% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
2.21% Hemolysis | 500 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 4 Activity

Activity

1.21% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
1.21% Hemolysis | 50 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 5 Activity

Activity

3.78% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
3.78% Hemolysis | 100 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 6 Activity

Activity

74.28% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
74.28% Hemolysis | 500 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 7 Activity

Activity

13.66% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
13.66% Hemolysis | 50 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 8 Activity

Activity

19.73% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
19.73% Hemolysis | 100 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 9 Activity

Activity

36.78% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
36.78% Hemolysis | 500 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 10 Activity

Activity

22.33% hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
22.33% hemolysis | 50 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 11 Activity

Activity

30.50% hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
30.50% hemolysis | 100 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018
Evidence 12 Activity

Activity

77% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
77% Hemolysis | 500 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Dilipid ultrashort cationic lipopeptides as adjuvants for chloramphenicol and other conventional antibiotics against Gram-negative bacteria. | Amino Acids | 2018