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Peptide record

TPDB26791

Antibacterial Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB26791
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
WXXLXXLLXXLXXL
Physicochemical Analysis
C41H67N7O7
ARNDCEQGHIKMFPSTYV
L
770.03
6.02
0
0
6
-0
-4.65
1.293
139.29
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
714.26
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C41H67N7O7
770.03
6.02
-0
-4.65
1.293
Evidence Records 1 records
Evidence 1 Activity

Activity

0.23% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
0.23% Hemolysis | 256 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii | Front Microbiol | 2021