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Peptide record

TPDB26757

Antibacterial Anticancer Hemolysis Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB26757
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
WWPFLRR
Physicochemical Analysis
C54H73N15O8
ANDCEQGHIKMSTYV
RW
1060.27
12.40
2
0
4
+2
-3.32
-0.829
55.71
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
1037.47
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
7
C54H73N15O8
1060.27
12.40
+2
-3.32
-0.829
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

inhibited Gram- S. typhimurium and E. coli less than the WT (diffusion assay). Warning: other bacteria not tested.
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
25.06 µM
Hemolytic Cytotoxic
10% Hemolysis | 25.06 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hybridization With Insect Cecropin A (1-8) Improve the Stability and Selectivity of Naturally Occurring Peptides. | Int J Mol Sci | 2020
Evidence 3 Activity

Activity

40% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
40% Hemolysis | 256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hybridization With Insect Cecropin A (1-8) Improve the Stability and Selectivity of Naturally Occurring Peptides. | Int J Mol Sci | 2020
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis