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Peptide record

TPDB26753

Antibacterial Anticancer Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB26753
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WWKKWKKWW
Physicochemical Analysis
C79H100N18O10
ARNDCEQGHILMFPSTYV
W
1461.78
11.00
4
0
5
+4
-5.29
-2.233
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
27500
1881.27
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
9
C79H100N18O10
1461.78
11.00
+4
-5.29
-2.233
Evidence Records 1 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
4% Hemolysis | 64 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Synthetic peptides that form nanostructured micelles have potent antibiotic and antibiofilm activity against polymicrobial infections. | Proc Natl Acad Sci U S A | 2023