Peptide record

TPDB26751

Antibacterial Antifungal Hemolysis Toxicity standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB26751
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 3-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
WWK
Physicochemical Analysis
C28H34N6O4
ARNDCEQGHILMFPSTYV
W
518.62
10.10
1
0
2
+1
-2.71
-1.900
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
2121.03
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
3
C28H34N6O4
518.62
10.10
+1
-2.71
-1.900
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
<<12.5 µM
Hemolytic Cytotoxic
50% Hemolysis | <<12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Small lipopeptides possess anti-biofilm capability comparable to daptomycin and vancomycin. | RSC Adv | 2015
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis